MovDisordV3, Main, Exploration, bibRecord, 000001

α7 nicotinic receptor agonists reduce levodopa-induced dyskinesias with severe nigrostriatal damage.

Identifieur interne : 000001 ( Main/Exploration ); précédent : 000000; suivant : 000002

α7 nicotinic receptor agonists reduce levodopa-induced dyskinesias with severe nigrostriatal damage.

Auteurs : Danhui Zhang [États-Unis] ; Matthew Mcgregor [États-Unis] ; Tanuja Bordia [États-Unis] ; Xiomara A. Perez [États-Unis] ; J Michael Mcintosh [États-Unis] ; Michael W. Decker [États-Unis] ; Maryka Quik [États-Unis]

Source :

Movement disorders : official journal of the Movement Disorder Society [ 1531-8257 ] ; 2015.

RBID : pubmed:26573698

Abstract

ABT-126 is a novel, safe, and well-tolerated α7 nicotinic receptor agonist in a Phase 2 Alzheimer's disease study. We tested the antidyskinetic effect of ABT-126 in 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-treated squirrel monkeys with moderate and more severe nigrostriatal damage.

DOI: 10.1002/mds.26453
PubMed: 26573698

Affiliations:

États-Unis
Californie, Illinois, Utah

Le document en format XML

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<front><div type="abstract" xml:lang="en">ABT-126 is a novel, safe, and well-tolerated α7 nicotinic receptor agonist in a Phase 2 Alzheimer's disease study. We tested the antidyskinetic effect of ABT-126 in 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-treated squirrel monkeys with moderate and more severe nigrostriatal damage.</div>
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<tree><country name="États-Unis"><region name="Californie"><name sortKey="Zhang, Danhui" sort="Zhang, Danhui" uniqKey="Zhang D" first="Danhui" last="Zhang">Danhui Zhang</name>
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<name sortKey="Bordia, Tanuja" sort="Bordia, Tanuja" uniqKey="Bordia T" first="Tanuja" last="Bordia">Tanuja Bordia</name>
<name sortKey="Decker, Michael W" sort="Decker, Michael W" uniqKey="Decker M" first="Michael W" last="Decker">Michael W. Decker</name>
<name sortKey="Mcgregor, Matthew" sort="Mcgregor, Matthew" uniqKey="Mcgregor M" first="Matthew" last="Mcgregor">Matthew Mcgregor</name>
<name sortKey="Mcintosh, J Michael" sort="Mcintosh, J Michael" uniqKey="Mcintosh J" first="J Michael" last="Mcintosh">J Michael Mcintosh</name>
<name sortKey="Perez, Xiomara A" sort="Perez, Xiomara A" uniqKey="Perez X" first="Xiomara A" last="Perez">Xiomara A. Perez</name>
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Movement Disorders (revue)

α7 nicotinic receptor agonists reduce levodopa-induced dyskinesias with severe nigrostriatal damage.

α7 nicotinic receptor agonists reduce levodopa-induced dyskinesias with severe nigrostriatal damage.

Source :

Abstract

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